Musc Videos

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Dr. Roger Newman is principal investigator for the national Standard for Normal Fetal Growth study at MUSC. Sponsored by the NIH, this new study will allow for a better determination of normal fetal growth based on individual maternal and fetal variables using ultrasounds instead of the previous standard of fundal height.

In this podcast some exciting new OBGYN research developments are reviewed by Dr. Roger Newman, Vice-Chair for Academic Affairs and Research at MUSC. Some of these studies include redefining what represents normal fetal growth in uncomplicated pregnancies, a study of preeclampsia by Drs. Chris Robinson and Donna Johnson, the affect of environmental marine health on reproductive outcomes and drug therapy during a pregnancy.

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At 41 years old, Don Holzheimer received a kidney from his brother after years of dealing with proteinuria, end stage renal disease and dialysis. In this podcast Don describes his experience undergoing dialysis, the kidney transplant procedure and recovery. He also explains why transplant patients take immunosuppressant drugs.

Don Holzheimer received a kidney transplant from his brother. Afterwards, he volunteered to participate in a clinical trial extending the use of a medication (ramipril) that has been used to control blood pressure to also control levels of protein in urine. This clinical trial also replaces calcineurin inhibitors (cyclosporine or Prograf) with sirolimus (Rapamune) to balance the effect of immunosuppressant medications. He has responded well to the medication and his doctor will be prescribing the use of this experimental mediation to continue. He reviews the experience of participating and the benefits of participating in a clinical trial.

In this podcast, Dr. Karen Hartwell explores the differences between men and women smokers. Based on these differences, she is researching different quitting treatment options using MRI scans and anticipates increasing the likelihood of permanent smoking cessation.

Dr. Istvan Takacs collaborated with Dr. Ziah Nahas to study the use of epidural prefrontal cortical stimulation for intractably depressed patients. Dr. Takacs discusses how this study began, the challenges turning their concept into a reality and the advantages of prefrontal cortical stimulation verses deep brain stimulation.

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Director of the Office of research Integrity, Dr. Robert Malcolm informs us of the recent AHRP accreditation awarded to MUSC and the Ralph Johnson VA Medical Center. He explains what AHRP is, why this accreditation is so important and the process involved in applying for the accreditation. He discusses the role of institutional review boards (IRB’s) and how the recent funding from the South Carolina Translational Research (SCTR) all help in safeguarding human research.

Dr. Ziad Nahas describes a ground-breaking treatment for severe, treatment resistant depression. In a study funded by NARSAD, Dr. Nahas and his colleagues implanted four small 'paddles' directly on the dural layer of the cortical brain surface, and over a period of seven months applied intermittent electrical stimulation through wires implanted beneath the skin connected to batteries. Four of the five patients had significant improvement in their symptoms of depression.

Dr. Tanya Turan discusses a clinical trial that is researching for answers to why some people develop hardening of the arteries inside the brain instead of other areas of the body. She also reviews qualifications for candidates that are interested in participating in this study.

Dr. Tanya Turan reviews this pilot study using an MRI scan to learn more about hardening of the arteries of the blood vessels in the brain. Through determining what the hardened particles in the brain are made of, this study could allow detection of increased risks of potential future stokes.

Dr. Tanya Turan’s clinical trial compares two different treatment options for stroke patients as a result of intercrainial stenosis or hardening of the arteries in the brain.