Cyanide Videos

Author: unikkatilkatolik Keywords: tba unikkatil noyzi duda tingulli albania kosova uck tirana prishtina lezha kuksi puka tropoja shkodra mirdita durrsi vlora fieri big brother presioni jeton Cyanide dmc babloki kobra dredha era corrupted tim soldier Added: November 1, 2009

Author: unikkatilkatolik Keywords: tba unikkatil noyzi duda tingulli albania kosova uck tirana prishtina lezha kuksi puka tropoja shkodra mirdita durrsi vlora fieri big brother presioni jeton Cyanide dmc babloki kobra dredha era corrupted tim soldier nag b52 Added: November 1, 2009

Author: unikkatilkatolik Keywords: tba unikkatil noyzi duda tingulli albania kosova uck tirana prishtina lezha kuksi puka tropoja shkodra mirdita durrsi vlora fieri big brother presioni jeton Cyanide dmc babloki kobra dredha era corrupted tim soldier nag b52 Added: November 1, 2009

AwesomeAuthor: TripleASR Tags: Metallica Cyanide DVD Nimes 2009 Posted: 07 October 2009 Rating: 0.0 Votes: 0

I was sweeping the floor in a clean vacant house in a small town, on the southern tip of Hawaii. The fine dust gathered together in sticky balls. When some was on my hand, it was very difficult to wash off. I decided to save it, and check it out. 3 weeks later I put it under my microscope (Sept. 27, 2009). I immediately saw many morgellons. This is the first time I have ever seen this. I had only used the microscope before to look at bug wings.Author: mrhelpfull Tags: morgellons chemtrails bio-weapons genocide mind control depopulation vaccine virus bacteria fungas ecoli cyanide Posted: 05 October 2009 Rating: 0.0 Votes: 0

The Cyanide and Happiness crew's newest and imho, best short to date. EnjoYRated 4.5669 / 5 | 2351 views | 12 comments Click here to watch the video Submitted By: Romuhdekips Tags: cyanide happiness waiting FOR the bus

Hitler and Eva attempt suicide. S4:Ep8.

Winner of the 2008 Uncle Dracula Monster Mashup 48 Hour Film Race Two Conspiracy Podcasters get in too deep when investigating the "Lizardo." The truth becomes all too real. Written, shot, and edited in 48 hours.

NO TABS, sorry... Lars Ulrich thank you, I'm honored: http://ca.youtube.com/watch?v=Dl2qocBpM1U ...hope you enjoy it....PLEASE don't ask for tabs, I don't have any, all by ear Recorded through a Pod X3 Live by Line 6 with my Ernie Ball Music Man John Petrucci Video edited with Sony Vegas 7

Taken from the accompanying DVD of the acclaimed 350 page underwater photography coffee table book REEF - Conserving Reefs is the ninth chapter that takes a long hard look at the threats that are far too often faced by the worlds REEFs.

The genes for the protein chains of hemoglobin show small differences within different human populations, so the amino acid sequence of hemoglobin is slightly different from person to person. In most cases the changes do not affect protein function and are often not even noticed. However, in some cases these different amino acids lead to major structural changes. One such example is that of the sickle cell hemoglobin, where glutamate 6 in the beta chain is mutated to valine. This change allows the deoxygenated form of the hemoglobin to stick to each other, as seen in PDB entry 2hbs, producing stiff fibers of hemoglobin inside red blood cells. This in turn deforms the red blood cell, which is normally a smooth disk shape, into a C or sickle shape. The distorted cells are fragile and often rupture, leading to loss of hemoglobin. This may seem like a uniformly terrible thing, but in one circumstance, it is actually an advantage. The parasites that cause the tropical disease malaria, which spend part of their life cycle inside red blood cells, cannot live in the fiber-filled sickle cells. Thus people with sickle cell hemoglobin are somewhat resistant to malaria. Other circumstances leading to troubled hemoglobins arise from a mismatch in the production of the alpha and beta proteins. The structure requires equal production of both proteins. If one of these proteins is missing, it leads to conditions called Thalassemia. You can look at the binding of oxygen up close in two structures of human hemoglobin. PDB entry 2hhb shows hemoglobin with no oxygen bound. In this picture, the heme is seen edge-on with the iron atom colored in gold. You can see the key histidine reaching up on the bottom side to bind to the iron atom. In PDB entry 1hho, oxygen has bound to the iron, pulling it upwards. This in turn, pulls on the histidine below, which then shifts the location of the entire protein chain. These changes are transmitted throughout the protein, ultimately causing the big shift in shape that changes the binding strength of the neighboring sites.

Cholera Toxin in Action The catalytic portion of cholera toxin performs a single function: it seeks out the G proteins used for cellular signaling and attaches an ADP molecule to them (for more on G-proteins, see the Molecule of the Month for March 2004 ). This converts the G-protein into a permanently active state, so it sends a never-ending signal. This confuses the cell, and among other things, it begins to transport lots of water and sodium outwards. This floods the intestine, leading to life-threatening dehydration. The two-part strategy employed by cholera toxin is highly effective, so much so that it is used by many different organisms that seek to protect themselves. A few examples from the PDB are shown here, with the targeting portion in blue and the toxic enzyme in red. These include E. coli enterotoxin (PDB entry 1ltb), which looks and acts like cholera toxin and is a cause of intestinal problems when traveling. Pertussis toxin (PDB entry 1prt), made by the bacterium that causes whooping cough, also attacks the G-protein signaling pathway. Diphtheria toxin (PDB entry 1mdt) is synthesized as a single chain, but is then cut to form the two-part toxin when it is released. It shuts down protein synthesis in cells by attacking one of the elongation factors. Ricin (PDB entry 2aai) is a powerful toxin made by the castor bean plant. Once it gets inside cells, it blocks protein synthesis by directly attacking ribosomes. For more information on toxins from a genomics perspective, take a look at the Protein of the Month at the European Bioinformatics Institute.